Taguchi K, Murashita J, Nakagaki M, Mochizuki T
World J Surg. 1980;4(2):251-9. doi: 10.1007/BF02393594.
An avcothanized vinyl sheet consisting of a Pall filter, 2 pressure monitoring lilnes, 2 heparinization lines, and a roller pump was used for transapical left ventricular bypass in 36 calves and 11 patients. Blood was returned to the abdominal or ascending aorta or carotid artery. Prolonged left ventricular flow unloading was carried out. All 31 calves that underwent left ventricular bypass and 5 calves that underwent left ventricular bypass and 5 calves that underwent biventricular bypass survived the scheduled period of bypass of up to 7 weeks except for 2 calves that died of accidental air embolism and 2 that were deliberately sacrificed due to infection. Local heparinization for 6 days followed by oral anticoagulation to maintain the prothrombin time at 150-200% of normal were effective in keeping the animals from bleeding and preventing thromboembolism. Eleven critically ill patients with severe heart disease were supported with left or biventricular bypass for periods of up to 172 hours. Four patients ultimately recovered, and 3 others were successfully weaned from bypass and expired 1-4 months later.
一种由颇尔过滤器、2条压力监测线、2条肝素化线和一个滚压泵组成的抗凝血乙烯基片用于36头小牛和11名患者的经心尖左心室旁路手术。血液回流至腹主动脉、升主动脉或颈动脉。进行了长时间的左心室流量卸载。除2头死于意外空气栓塞和2头因感染而被故意处死的小牛外，所有31头接受左心室旁路手术的小牛以及5头接受左心室旁路手术和5头接受双心室旁路手术的小牛均存活至长达7周的预定旁路手术期。局部肝素化6天，随后口服抗凝剂以将凝血酶原时间维持在正常的150 - 200%，有效地防止了动物出血和血栓栓塞。11名患有严重心脏病的重症患者接受了左心室或双心室旁路支持，时间长达172小时。4名患者最终康复，另外3名患者成功脱离旁路，但在1 - 4个月后死亡。
