Gurwitz D, Corey M, Levison H
Am Rev Respir Dis. 1980 Jul;122(1):95-9. doi: 10.1164/arrd.1980.122.1.95.
Ninety-six children who were admitted into hospital with croup 8.5 yr previously were studied to assess lung function, atopic disease, and bronchial reactivity. Although absolute values in pulmonary function showed only small differences, children who have had croup are members of a population that is significantly different from normal children. Thirty-five per cent had heightened bronchial reactivity, as determined by methacholine challenge. There was no increased incidence of atopic disease in the children studied. One can speculate that these children who have had croup may be a population susceptible to developing chronic obstructive airway disease as adults.
对8.5年前因患哮吼住院的96名儿童进行了研究，以评估其肺功能、特应性疾病和支气管反应性。尽管肺功能的绝对值仅显示出微小差异，但患过哮吼的儿童与正常儿童存在显著差异。通过乙酰甲胆碱激发试验确定，35%的儿童支气管反应性增强。在所研究的儿童中，特应性疾病的发病率没有增加。可以推测，这些患过哮吼的儿童成年后可能易患慢性阻塞性气道疾病。
