Bergdahl D M, Stevenson J G, Kawabori I, Guntheroth W G
Circulation. 1980 Oct;62(4):897-901. doi: 10.1161/01.cir.62.4.897.
Five male pediatric patients with primary ventricular tachycardia are described. Although three were initially in congestive heart failure due to the tachycardia and were extremely difficult to manage, all have completely recovered, are not taking medication, and are free of arrhythmia. Three of the patients required long-term management with quinidine, with a therapeutic goal of controlling the heart rather than abolishing the arrhythmia. No growth disturbances were found in those three patients. A review of reported cases revealed 71 infants and children with ventricular tachycardia not associated with heart disease or systemic disorders; only four deaths were reported (5.6%). In the primary form of ventricular tachycardia in children, complete pharmacologic suppression may not be achieved without seriously endangering the normal electrophysiologic functions. Controlling the rate to an asymptomatic level with pharmacologic means is safer for a problem that may be self-limited.
本文描述了5例原发性室性心动过速的男性儿科患者。尽管其中3例最初因心动过速而出现充血性心力衰竭，且极难处理，但所有患者均已完全康复，未服用药物，且无心律失常。3例患者需要长期使用奎尼丁进行治疗，治疗目标是控制心率而非消除心律失常。这3例患者未发现生长发育障碍。对已报道病例的回顾显示，有71例婴儿和儿童患有与心脏病或全身性疾病无关的室性心动过速；仅报道了4例死亡（5.6%）。在儿童原发性室性心动过速中，若不严重危及正常电生理功能，可能无法实现完全的药物抑制。对于可能自限性的问题，采用药物手段将心率控制在无症状水平更为安全。
