Yoshida K, Shiina A, Asano Y, Hosoda S
Clin Nephrol. 1980 Jun;13(6):260-8.
Echocardiography (UCG) was performed prior to and during hemodialysis therapy to detect and evaluate volumetrically the grade of pericardial effusion in 150 patients with chronic renal failure. The actual incidence of uremic pericardial effusion during the observation period was 62% and was higher during the first 3 months of therapy than at later stages. Pericardial effusion was classified from grade 0 (no effusion) to grade 5 (massive effusion). We compared the grade of effusion with laboratory test results, blood pressure, cardiothoratic ratio, left atrial and ventricular dimensions, and thickness of the intraventricular septum and left ventricular posterior wall. Significant differences between the patients with and without effusion were detected in the degree of systolic hypertension, dilatation of the left atrial chamber, anemia and hypoproteinemia. There was no correlation between the grade of effusion and creatinine, uric acid and calcium levels and changes of body weight. Our results confirm that insufficient dialysis as indexed by the degree of hypoproteinemia, anemia, hypertension and central overhydration, may play a role in the etiology of uremic pericardial effusion.
在150例慢性肾衰竭患者进行血液透析治疗前及治疗期间，进行了超声心动图（UCG）检查，以检测并定量评估心包积液的程度。观察期内尿毒症心包积液的实际发生率为62%，且在治疗的前3个月高于后期。心包积液从0级（无积液）到5级（大量积液）进行分类。我们将积液程度与实验室检查结果、血压、心胸比率、左心房和心室大小以及室间隔和左心室后壁厚度进行了比较。有积液和无积液患者在收缩期高血压程度、左心房扩大、贫血和低蛋白血症方面存在显著差异。积液程度与肌酐、尿酸、钙水平及体重变化之间无相关性。我们的结果证实，以低蛋白血症、贫血、高血压和中枢性水过多程度为指标的透析不充分，可能在尿毒症心包积液的病因中起作用。
