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用铟 - 111标记的供体粒细胞评估中性粒细胞减少患者的感染情况。

Evaluation of infection in neutropenic patients with indium-111-labeled donor granulocytes.

作者信息

Alavi J B, Alavi A, Staum M M

出版信息

Clin Nucl Med. 1980 Sep;5(9):397-400. doi: 10.1097/00003072-198009000-00002.

DOI:10.1097/00003072-198009000-00002
PMID:7408356
Abstract

Donor granulocytes, obtained by filtration leukophoresis, were labeled with In-111-oxine and injected into seven severely neutropenic patients. All patients were febrile, and presumed to have infection, although infection was eventually proved in only five. Excellent demonstration of infection was achieved in two patients, and fair localization in one. One negative scan became positive when repeated with sedimentation-derived cells from a different donor. This method may be useful in detecting infections in neutropenic patients.

摘要

通过过滤白细胞去除法获得的供体粒细胞,用铟 - 111 - 奥克辛进行标记,并注入7名严重中性粒细胞减少的患者体内。所有患者均发热,推测有感染,尽管最终仅在5名患者中证实有感染。在2名患者中对感染有良好的显示,在1名患者中定位尚可。当用来自不同供体的沉降细胞重复扫描时,1次阴性扫描变为阳性。该方法可能有助于检测中性粒细胞减少患者的感染。

相似文献

1
Evaluation of infection in neutropenic patients with indium-111-labeled donor granulocytes.用铟 - 111标记的供体粒细胞评估中性粒细胞减少患者的感染情况。
Clin Nucl Med. 1980 Sep;5(9):397-400. doi: 10.1097/00003072-198009000-00002.
2
Donor-leukocyte imaging in granulocytopenic patients with suspected abscesses: concise communication.
J Nucl Med. 1982 Apr;23(4):319-21.
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Re: Decreased sensitivity of early imaging with in-111 oxine-labeled leukocytes in detection of occult infection.
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[Diagnosis of internal abscesses by scintigraphy: results of a method using purified granulocytes].[通过闪烁扫描术诊断内部脓肿:使用纯化粒细胞的方法的结果]
Schweiz Med Wochenschr. 1983 Oct 8;113(40):1477-9.
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Comparison of leukocytes labeled with indium-111-2-mercaptopyridine-N-oxide and indium-111 oxine for abscess detection.用于脓肿检测的铟-111-2-巯基吡啶-N-氧化物标记白细胞与铟-111 喹啉的比较。
J Nucl Med. 1987 Apr;28(4):438-41.
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Diagnosis of Salmonella osteomyelitis in a neutropenic patient using 111indium-labelled donor leucocytes.使用铟-111标记的供体白细胞诊断中性粒细胞减少患者的沙门氏菌骨髓炎。
Clin Lab Haematol. 1985;7(2):177-81. doi: 10.1111/j.1365-2257.1985.tb00023.x.
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Indium 111 autologous leucocyte scanning in lobar pneumonia and lung abscesses.铟111标记自体白细胞扫描在大叶性肺炎和肺脓肿中的应用
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A simple method of granulocyte enrichment of crude white cell suspensions labelled with 111In.一种对用铟-111标记的粗制白细胞悬液进行粒细胞富集的简单方法。
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Indium-111-labeled leukocyte localization in hematomas: a pitfall in abscess detection.
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Indium-111 white blood cell scan for infectious complications of polycystic renal disease.铟-111白细胞扫描用于多囊肾疾病的感染性并发症
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