Alavi J B, Alavi A, Staum M M
Clin Nucl Med. 1980 Sep;5(9):397-400. doi: 10.1097/00003072-198009000-00002.
Donor granulocytes, obtained by filtration leukophoresis, were labeled with In-111-oxine and injected into seven severely neutropenic patients. All patients were febrile, and presumed to have infection, although infection was eventually proved in only five. Excellent demonstration of infection was achieved in two patients, and fair localization in one. One negative scan became positive when repeated with sedimentation-derived cells from a different donor. This method may be useful in detecting infections in neutropenic patients.
通过过滤白细胞去除法获得的供体粒细胞,用铟 - 111 - 奥克辛进行标记,并注入7名严重中性粒细胞减少的患者体内。所有患者均发热,推测有感染,尽管最终仅在5名患者中证实有感染。在2名患者中对感染有良好的显示,在1名患者中定位尚可。当用来自不同供体的沉降细胞重复扫描时,1次阴性扫描变为阳性。该方法可能有助于检测中性粒细胞减少患者的感染。