Foussereau J, Meynadier J, Reuter G, Herve-Bazin B, Cavelier C
Derm Beruf Umwelt. 1980;28(2):41-4.
The coming out of 20 cases of eczema to American cloth, in 1978, motivated a clinical, allergologic and chemical investigation. From a clinical point of view, the lesions were located in areas in contact with American cloth. Cutaneous biopsies, which were carried out in 3 cases, established the allergic eczematous nature of these lesions. Epicutaneous tests were carried out by these patients. With American cloth, results were positive in 20 cases out of 20; six constituents provided by the manufacturer and a standard battery of allergens gave no indication. The chemical analysis of American cloths revealed among others an unknown product which was found in every formulation. This product had a molecular weight of 223; the infra-red spectra and the mass spectra showed a strong analogy with the spectra of alpha-phenyl indole. Tests carried out with alpha-phenyl-indole were positive in 11 cases out of 18; among controls every test was negative.
1978年，20例因接触美国布料而引发湿疹的病例促使人们开展了一项临床、变态反应学及化学方面的调查。从临床角度来看，皮损位于与美国布料接触的部位。对3例患者进行了皮肤活检，确定了这些皮损具有过敏性湿疹的性质。这些患者接受了皮肤试验。用美国布料进行试验时，20例患者中有20例结果呈阳性；制造商提供的六种成分以及一组标准变应原均无反应。对美国布料的化学分析发现，每种配方中都有一种未知产品。该产品的分子量为223；红外光谱和质谱显示与α-苯基吲哚的光谱有很强的相似性。用α-苯基吲哚进行的试验，18例中有11例呈阳性；对照组的各项试验均为阴性。
