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鲍温样丘疹病(作者译)

[Bowenoid papulosis (author's transl)].

作者信息

Tritsch H

出版信息

Dtsch Med Wochenschr. 1980 Jun 20;105(25):887-91. doi: 10.1055/s-2008-1070775.

Abstract

Bowenoid papulosis of the anogenital area was found in 3 women and 3 men aged 24 to 64 years. These were papulo-verrucous efflorescences with a tendency to multilocular recurrences despite cold cauterisation. Spontaneous healing was also observed. Histology showed acanthomas with varying degrees of dysplasia including carcinoma in situ. Light microscopic changes in the proliferating epidermis were found repeatedly which is taken as evidence for virus-induced origin. Thus the characteristic cell dysplasia of bowenoid papulosis is possibly the consequence of a viral anaplastic transformation. There is no definite histologic differentiation between dysplasia due to podophyllin in papillary condylomas and that of bowenoid papulosis.

摘要

在3名年龄为24至64岁的女性和3名男性中发现了肛门生殖器部位的鲍温样丘疹病。这些是丘疹疣状皮疹,尽管进行了冷冻烧灼,仍有多发复发的倾向。也观察到了自发愈合。组织学显示有不同程度发育异常的棘皮瘤,包括原位癌。在增殖的表皮中反复发现光镜下的变化,这被视为病毒诱导起源的证据。因此,鲍温样丘疹病特征性的细胞发育异常可能是病毒间变转化的结果。乳头瘤状湿疣中因鬼臼毒素导致的发育异常与鲍温样丘疹病的发育异常在组织学上没有明确的区分。

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