Anomalous pigment epithelial photoreceptor relationships and receptor orientation.

In order to further investigate the factors influencing retinal receptor orientation, three patients with local disturbances of the receptor/pigment epithelium (PE) interface have been evaluated. Psychophysical and clinical tests have been used to characterize the observed abnormalities. The following conclusions are made. Receptor orientation is lost following a serous detachment of the neurosensory retina and can recover following reattachment of the retina. Orientation may be retained despite the presence of serous detachment of the PE, loss of the light/dark component of the electro-oculogram, and vitelliform-like lesions between the receptors and the PE.