Sesma P
Rev Esp Fisiol. 1978 Dec;34(4):423-7.
When mice are injected with trypan blue inside the peritoneal cavity immediately after birth, a delay of the lymphocyte colonization and an enhancement of the lymph node myelopoiesis are observed. In normal mice some granulopoiesis takes place in lymph nodes between 4th and 12th days after birth, but after trypan blue treatment granulopoiesis increases and erythroid colonies appear. These findings indicate that the blockade of RES enhances the hemopoiesis in lymph nodes.
当在出生后立即向小鼠腹腔内注射台盼蓝时,可观察到淋巴细胞定居延迟以及淋巴结髓系造血增强。在正常小鼠中,出生后第4天至第12天期间,淋巴结会发生一些粒细胞生成,但在台盼蓝处理后,粒细胞生成增加且出现红系集落。这些发现表明,网状内皮系统的阻断增强了淋巴结中的造血作用。