González-Barón S, Molina M, Bogas A M, García Matilla F
Rev Esp Fisiol. 1978 Dec;34(4):463-72.
Larynx resistance changes have been studied in the dog by means of in situ isolated glottis technique. Bronchiolar tone changed through isoprenaline and histamine administration, and after recurrent and vagus nerve bilateral section. Isoprenaline administration (0.1 mg/kg) was followed by larynx resistance decrease, expiratory duration increase, and expiratory abdominal pressure decrease with regard to respiration preceded by rest. Cough response by mechanical tracheal stimulation and glottis closing by larynx stimulation were abolished after isoprenaline administration. Histamine administration (0.1 mg/kg) was followed by larynx resistance increase, expiratory duration decrease, expiratory abdominal pressure increase, and expiratory abdominal pressure/maximum expiratory airflow relation increase. Larynx resistance decreased after recurrent nerve bilateral section, and increased later when vagus nerves were sectioned.
已通过原位孤立声门技术在犬身上研究了喉阻力变化。通过给予异丙肾上腺素和组胺,以及在双侧切断喉返神经和迷走神经后,细支气管张力发生了变化。给予异丙肾上腺素(0.1mg/kg)后,与静息前的呼吸相比,喉阻力降低、呼气持续时间延长、呼气腹部压力降低。给予异丙肾上腺素后,机械性气管刺激引起的咳嗽反应和喉部刺激引起的声门关闭被消除。给予组胺(0.1mg/kg)后,喉阻力增加、呼气持续时间缩短、呼气腹部压力增加,且呼气腹部压力/最大呼气气流关系增加。双侧切断喉返神经后喉阻力降低,随后切断迷走神经时喉阻力增加。