Popov A V, Kuznetsov A S, Vinogradov A G
Kardiologiia. 1980 Aug;20(8):38-42.
Atherogenic lipoproteins are present in the aortic wall in complexes with various glycosaminoglycans. Reduced uptake of 125I-lipoproteins of low density by the foam cells and diminished respiration-stimulating effect of low-density lipoproteins on the cells under the influence of glycosaminoglycans reflects the capacity of glycosaminoglycans for changing the physico-chemical properties of lipoproteins in the direction of a decrease in their interaction with the foam cells.
致动脉粥样硬化脂蛋白以与各种糖胺聚糖结合的复合物形式存在于主动脉壁中。在糖胺聚糖的影响下,泡沫细胞对125I标记的低密度脂蛋白摄取减少,且低密度脂蛋白对细胞的呼吸刺激作用减弱,这反映了糖胺聚糖能够改变脂蛋白的物理化学性质,使其与泡沫细胞的相互作用减弱。