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双白蛋白血症与假性双白蛋白血症:临床意义(作者译)

[Bisalbuminemia and pseudobisalbuminemia: clinical significance (author's transl)].

作者信息

Gómez Agudo G, Cuesta Muñóz J, Hortells Aznar J L, Orden Gonzalo I, Giner Soria A, Franco Alcalde L

出版信息

Med Clin (Barc). 1980 May 25;74(10):399-402.

PMID:7412433
Abstract

Two cases of bisalbuminaemia are hereby studied: a congenital case and an acquired or transitory case. In the first one, this hereditary disturbance is studied on four affected members of one Spanish family, being associated in two of them with multiple lipomatosis. This kind of association is considered as casual. As in most of the informed cases, ours belongs to the slow kind. The second case deals with a bisalbuminaemia of transitory character or pseudobisalbuminaemia which, appeared in a woman in the course of an acute pancreatitis of biliolithiasic origin, with a pancreatic pseudocyst and pleural effusion, the evolution in the inflamatory pancreatic process being advantageous in spite of the prsence of bisalbuminaemia. Briefly revised, are exposed the causes of this interesting and rare alteration in the electrophoretic fractioning of plasmatic proteins: congenital, and adquired causes due to administration of betalactamines and during the course of acute pancreatitis.

摘要

在此研究了两例双白蛋白血症病例

一例先天性病例和一例后天性或暂时性病例。在第一例中,对一个西班牙家庭的四名受影响成员进行了这种遗传性疾病的研究,其中两人伴有多发性脂肪瘤病。这种关联被认为是偶然的。与大多数已知病例一样,我们的病例属于缓慢型。第二例涉及一例暂时性双白蛋白血症或假性双白蛋白血症,该病例出现在一名患有胆石症源性急性胰腺炎、伴有胰腺假性囊肿和胸腔积液的女性身上,尽管存在双白蛋白血症,但胰腺炎症过程的进展是有利的。简要回顾了血浆蛋白电泳分离中这种有趣且罕见变化的原因:先天性原因,以及因使用β-内酰胺类药物和在急性胰腺炎过程中导致的后天性原因。

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