[5-氮杂胞苷的临床应用可能性]

Vopr Onkol. 1977;23(10):65-73.

The authors report the structure and mechanism of 5-azacytidine action. This drug was first synthesized in the Institute of Organic Chemistry and Biochemistry of Czechoslovak Academy of Sciences (Prague) and used experimentally for leukemia L1210 and leukemic AKR mice and clinically for treatment of acute leukemia in children, in particular.

作者报道了5-氮杂胞苷的作用结构和机制。这种药物最初由捷克斯洛伐克科学院有机化学和生物化学研究所（布拉格）合成，并在实验中用于白血病L1210和白血病AKR小鼠，临床上尤其用于治疗儿童急性白血病。