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[小鼠肿瘤中起源于外胚层的交叉反应性上皮抗原]

[Cross-reacting epithelial antigen of ectodermal origin in mouse tumors].

作者信息

Beletskaia L V, Gnezditskaia E V, Raĭkhlin N T, Borodniuk N A, Rassokhina I I

出版信息

Vopr Onkol. 1977;23(10):83-7.

PMID:74128
Abstract

Cross-reacting antigen (CR-antigen) previously found by indirect immunofluorescence in cell elements of murine multilayer epithelial cells (except corneal epithelium) to play the role of antigenic label of cover epithelia of ectodermal origin was found in mice tumor cells, related histogenetically with multilayer epithelium (transplantable proventricular cancer, two strains of squamous-cell cervical cancer in mice). CR-antigen was observed in transplantable breast adenocarcinoma and in transplantable mice teratocarcinoma.

摘要

先前通过间接免疫荧光法在小鼠复层上皮细胞(角膜上皮除外)的细胞成分中发现的交叉反应抗原(CR抗原),可作为外胚层来源覆盖上皮的抗原标记物,在与复层上皮有组织发生学关系的小鼠肿瘤细胞中也被发现(可移植的前胃腺癌、两株小鼠鳞状细胞宫颈癌)。在可移植的乳腺腺癌和可移植的小鼠畸胎瘤中也观察到了CR抗原。

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