Salafia W R, Allan A M
Physiol Behav. 1980 Jun;24(6):1047-51. doi: 10.1016/0031-9384(80)90045-1.
The effects of hippocampal stimulation on the development and expression of latent inhibition were investigated employing classical conditioning of the nictitating membrane response of rabbits. Hippocampal stimulation overlapping conditioned stimulus preexposure produced attenuation of latent inhibition, as did stimulation presented during conditioning after preexposure. However, hippocampal stimulation during conditioning in the absence of preexposure had little effect. The results support the hypotheses that in classical conditioning a major function of the hippocampus is the modulation of sensory input, especially input involved in the learned irrelevance of stimuli.
利用兔瞬膜反应的经典条件反射,研究了海马刺激对潜伏抑制的发展和表达的影响。与条件刺激预暴露重叠的海马刺激会导致潜伏抑制减弱,预暴露后在条件反射期间进行的刺激也会如此。然而,在没有预暴露的条件反射期间进行海马刺激几乎没有效果。这些结果支持了以下假设:在经典条件反射中,海马的主要功能是调节感觉输入,特别是涉及已习得的刺激无关性的输入。