Greco R S, Rubin R, Salvati E
Surg Gynecol Obstet. 1980 Oct;151(4):471-6.
Leukocyte migration inhibition assays in patients with carcinoma of the colon and rectum were evaluated in patients treated by electrocoagulation, abdominoperineal resection or low anterior resection and those with Duke's A and B lesions. Assays were performed before treatment, immediately after treatment and two to four months later. No statistically significant differences in cell mediated immunity, measured by leukocyte migration inhibition, were noted between those in the electrocoagulated group and those undergoing resection. However, electrocoagulation does appear to cure some carcinomas of the rectum and does afford a superior quality of survival. It is, however, associated with a higher recurrence rate than resection. Therefore, the decision to use electrocoagulation should not be based upon its effect on immune parameters. Rather, the choice between electrocoagulation, local resection and abdominoperineal resectin is based upon clinical judgment in which the risk of recurrence or metastases must be weighed against a superior quality of survival.
对接受电凝术、腹会阴切除术或低位前切除术治疗的结肠癌和直肠癌患者以及患有杜克A期和B期病变的患者进行了白细胞迁移抑制试验。在治疗前、治疗后即刻以及两到四个月后进行试验。通过白细胞迁移抑制测量的细胞介导免疫方面，电凝组患者与接受切除术的患者之间未观察到统计学上的显著差异。然而，电凝术似乎确实能治愈一些直肠癌，并且确实能提供更高的生存质量。然而，它的复发率高于切除术。因此，决定使用电凝术不应基于其对免疫参数的影响。相反，在电凝术、局部切除术和腹会阴切除术之间的选择基于临床判断，其中必须权衡复发或转移的风险与更高的生存质量。
