Lukashkov V M, Maianskiĭ A N
Zh Mikrobiol Epidemiol Immunobiol. 1980 Mar(3):75-8.
The immunological interrelations between the protein complexes of 34 strains of 12 species belonging to the family Neisseriaceae were studied with the use of delayed hypersensitivity reactions in specifically sensitized guinea pigs. No statistically significant differences between the nonpathogenic species of the family Neisseriaceae and the strains of N. haemolysans, n. cuniculi, N. lactamicus, N. ovis, N. elongata, N. cinerea were revealed. The preparations of Branhamella catarrhalis and N. caviae gave weak cross reactions with each other, as well as with other Neisseria. The probability and intensity of delayed hypersensitivity cross reactions depended on the degree of the immunological affinity of the preparations. The immunological similarity of protein complexes in most of the representatives of the family Neisseriaceae presents great possibilities for the development of sensitization to this group of microorganisms.
利用特异性致敏豚鼠的迟发型超敏反应，研究了奈瑟菌科12个种34株菌株蛋白质复合物之间的免疫相互关系。未发现奈瑟菌科非致病性种与溶血奈瑟菌、兔奈瑟菌、产乳酸奈瑟菌、羊奈瑟菌、长奈瑟菌、灰色奈瑟菌菌株之间存在统计学上的显著差异。卡他布兰汉菌和豚鼠奈瑟菌的制剂彼此之间以及与其他奈瑟菌之间产生微弱的交叉反应。迟发型超敏交叉反应的概率和强度取决于制剂的免疫亲和程度。奈瑟菌科大多数代表菌株蛋白质复合物的免疫相似性为对这组微生物致敏的发展提供了很大可能性。
