[A群链球菌细胞壁非特异性蛋白质抗原在迟发型超敏反应发生中的作用]
[The role of non-type-specific protein antigens of the cell wall in Streptococcus group A in developing delayed hypersensitivity].
作者信息
Bazanova E A, Bukhova V P, Liampert I M
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1987 Aug(8):67-71.
The role of the type-nonspecific (TNS) cell-wall antigens of group A streptococci has been determined. The study has been made on guinea pigs sensitized with whole microbial cells or HCl extracts containing TNS antigens. To determine delayed hypersensitivity, the in vitro cytotoxic test on adhering lymph-node cells in the autologous system has been used. The study has shown that sensitization with group A streptococci of different types or with TNS antigens induces the development of delayed hypersensitivity to TNS antigens (or antigen), common for different types of group A streptococci, but specific for this group. HCl extracts containing TNS antigens can be recommended as the preparation for testing delayed hypersensitivity to antigens, specific for group A streptococci.
A群链球菌的非特异性（TNS）细胞壁抗原的作用已被确定。该研究是在经全微生物细胞或含有TNS抗原的盐酸提取物致敏的豚鼠身上进行的。为了确定迟发型超敏反应，采用了自体系统中对黏附淋巴结细胞的体外细胞毒性试验。研究表明，用不同类型的A群链球菌或TNS抗原致敏可诱导对TNS抗原（或抗原）产生迟发型超敏反应，这种反应对于不同类型的A群链球菌是共同的，但对该菌群具有特异性。含有TNS抗原的盐酸提取物可被推荐作为检测对A群链球菌特异性抗原迟发型超敏反应的制剂。
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