Shutov A A, Chudinov A A, Pleshkova N M
Zh Vopr Neirokhir Im N N Burdenko. 1980 May-Jun(3):23-7.
The amount of the pituitary thyrotropic hormone and the thyroid hormones (T4, T3, KET) in the serum of 30 patients with severe craniocerebral trauma was studied in dynamics from the 1st and until the 30th day of the disease. Marked disorders in the hypothalamo-hypophyseal-thyroid system were revealed in the form of hypersecretion of the thyrotropic hormone and profound inhibition of the thyroid function. Both the transport-organic and the metabolic phase of metabolism of the thyroid hormones suffer, with prevalent changes in the former. Disturbed thyroid metabolism is an essential link in the pathogenesis of a severe craniocerebral trauma and calls for the corresponding correction.
对30例重型颅脑创伤患者血清中的垂体促甲状腺激素及甲状腺激素（T4、T3、KET）水平在发病第1天至第30天进行了动态研究。结果发现下丘脑 - 垂体 - 甲状腺系统存在明显紊乱，表现为促甲状腺激素分泌过多以及甲状腺功能受到严重抑制。甲状腺激素代谢的转运 - 有机相和代谢相均受影响，其中前者变化更为普遍。甲状腺代谢紊乱是重型颅脑创伤发病机制中的一个重要环节，需要进行相应的纠正。
