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小鼠肺内的肺泡间孔。区域分布及随年龄的变化

Interalveolar pores in mouse lung. Regional distribution and alterations with age.

作者信息

Ranga V, Kleinerman J

出版信息

Am Rev Respir Dis. 1980 Sep;122(3):477-81. doi: 10.1164/arrd.1980.122.3.477.

DOI:10.1164/arrd.1980.122.3.477
PMID:7416622
Abstract

Quantitative analysis of the regional distribution of interalveolar pores in the lungs of BALB/c mice 1 to 28 months of age (n = 25) was performed by scanning electron microscopy. In all the age groups examined, the subpleural and peribronchiolar alveoli had significantly more pores than the midzonal region (p < 0.01). No significant changes were noted in the number of pores per alveolus between 3 and 26 months of age in the midzonal, peribronchiolar, and subpleural alveoli. We concluded that (1) intralevolar pores are regionally distributed in the lungs of BALB/c mice by 3 months of age, and (2) the number of pores do not significantly change with increasing age during the first 26 months.

摘要

通过扫描电子显微镜对1至28月龄BALB/c小鼠(n = 25)肺内肺泡间孔的区域分布进行了定量分析。在所有检查的年龄组中,胸膜下和细支气管周围的肺泡比肺中区有明显更多的孔(p < 0.01)。在3至26月龄期间,肺中区、细支气管周围和胸膜下肺泡的每个肺泡孔数量没有显著变化。我们得出结论:(1)到3月龄时,BALB/c小鼠肺内的肺泡内孔呈区域分布;(2)在最初的26个月中,孔的数量不会随着年龄的增长而显著变化。

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