Tonndorf J
Ann Otol Rhinol Laryngol. 1980 Jul-Aug;89(4 Pt 1):353-8. doi: 10.1177/000348948008900411.
The combination of hearing loss, recruitment, poor speech discrimination and tinnitus, which is characteristic of acute cochlear disorders, can be accounted for on the basis of a decoupling of hair cells from their drive system, the tectorial membrane. Decoupling may either be caused by a temporary reduction of ciliary stiffness (shown to occur during periods of noise-induced temporary threshold shifts) or by temporary and/or chronic ciliary pathology (demonstrated to exist in cases of antibiotic ototoxicity and in endolymphatic hydrops). Since ciliary coupling is elastic in nature, the decoupling is only partial. The hearing loss and the tinnitus are manifestations of the reduced coupling per se, the magnitude of the loss depending on the degree of decoupling and the number of hair cells involved. Recruitment and poor speech discrimination result from center-clipping of the signal waveform applied to an involved hair cell, the direct corollary of partial, ciliary decoupling.
听力损失、重振、言语辨别力差和耳鸣相结合，是急性耳蜗疾病的特征，这可以基于毛细胞与其驱动系统（盖膜）的解耦来解释。解耦可能是由睫状肌刚度暂时降低（已证实在噪声引起的暂时阈移期间会发生）或由暂时和/或慢性睫状肌病变（已证实在抗生素耳毒性和内淋巴积水病例中存在）引起的。由于睫状耦合本质上是有弹性的，所以解耦只是部分的。听力损失和耳鸣是耦合本身降低的表现，损失的程度取决于解耦的程度和所涉及的毛细胞数量。重振和言语辨别力差是由于施加到受累毛细胞的信号波形的中心削波导致的，这是部分睫状解耦的直接结果。
