Dobrynin Y V, Vyshinskaya G V
Antibiot Chemother (1971). 1980;28:13-4. doi: 10.1159/000386053.
The incorporation of 3H-thymidine into DNA in short-term human tumor cultures under the effect of antitumor drugs have been investigated. The method was used to test different malignant tumors in 104 patients. 53 patients were treated with different drugs and the results of this administration were analyzed. In 88.7% of cases, correlation was shown between the laboratory drug sensitivity testing and clinical response.
研究了在抗肿瘤药物作用下,短期培养的人肿瘤细胞中3H-胸腺嘧啶核苷掺入DNA的情况。该方法用于检测104例患者的不同恶性肿瘤。53例患者接受了不同药物治疗,并对给药结果进行了分析。在88.7%的病例中,实验室药物敏感性测试与临床反应之间存在相关性。