Malysheva S F, Romanova O A, Slivinskaia Z P
Vopr Onkol. 1978;24(11):30-5.
Under examination was the possibility to reveal clinico-immunological features in patients with soft tissue sarcomas prior to and after surgery. Different immune responses were observed in patients with various forms of tumor progression. In case of a favourable course of the process surgery somewhat stimulates the cell immune response and reduces the titre of humoral antibodies. In patients with the tumor progression despite the employed treatment, a gradual fall of high cell immunity indices with a simultaneous increase of the humoral antibodies titre was noted. Wide metastases spread in the terminal phase is manifested by suppression of the immune response.
研究了在软组织肉瘤患者手术前后揭示临床免疫特征的可能性。在不同形式肿瘤进展的患者中观察到了不同的免疫反应。在病情进展顺利的情况下,手术在一定程度上刺激细胞免疫反应并降低体液抗体滴度。在尽管接受了治疗但仍有肿瘤进展的患者中,注意到高细胞免疫指标逐渐下降,同时体液抗体滴度升高。终末期广泛转移的扩散表现为免疫反应受到抑制。