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[免疫反应在评估软组织肉瘤疾病预后中的作用]

[Immune reactions in assessing the disease prognosis in soft tissue sarcomas].

作者信息

Klimenkov A A, Kadagidze Z G, Gladikov Iu V

出版信息

Vopr Onkol. 1979;25(1):3-8.

PMID:425395
Abstract

Under examination were 60 patients with local forms of soft tissue sarcomas of various histological structure. By means of skin delayed hypersensitivity test for dinitrochlorobenzene (DNCB) and tuberculin as well as cell immunity reaction in vitro the immune response was shown to be of value in estimating the prognosis of the disease. The dynamics of immune reactions 2-3 months following the operation proved to be of greatest prognostic value. Among the employed immunological tests the skin test for DNCB and the reaction of spontaneous rosette-forming provided the most comprehensive information as to the control over the clinical course of malignant lesion.

摘要

对60例具有各种组织学结构的软组织肉瘤局部型患者进行了检查。通过二硝基氯苯(DNCB)和结核菌素皮肤迟发型超敏反应试验以及体外细胞免疫反应,发现免疫反应在评估疾病预后方面具有重要价值。术后2 - 3个月免疫反应的动态变化被证明具有最大的预后价值。在所采用的免疫学检测中,DNCB皮肤试验和自发玫瑰花结形成反应能提供关于恶性病变临床进程控制的最全面信息。

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