Städtler P, Sulzer M, Petrin P
Wien Klin Wochenschr. 1978 Dec 8;90(23):844-7.
The present state of knowledge regarding the aetiology of caries implicates the interrelationship between low-molecular carbohydrates and the bacterial flora as an essential factor in the potential development of caries. Persons with hereditary fructose intolerance and patients with diabetes mellitus are of special interest in studying these interrelations. The DMF/S index was calculated and a regression analysis carried out in 101 diabetic children and juveniles aged 4 to 18. The incidence of dentine caries was significantly lower in children with onset of diabetes preceding the appearance of the second dentition than in children with manifest diabetes of up to 3 years' duration. The DMF/S index was high in individual patients in spite of the prescribed dietary treatment.
目前关于龋齿病因的知识状况表明，低分子碳水化合物与细菌菌群之间的相互关系是龋齿潜在发展的一个重要因素。患有遗传性果糖不耐受症的人和糖尿病患者在研究这些相互关系时具有特殊意义。对101名4至18岁的糖尿病儿童和青少年计算了DMF/S指数并进行了回归分析。在恒牙萌出前就患糖尿病的儿童中，牙本质龋的发生率明显低于病程长达3年的显性糖尿病儿童。尽管进行了规定的饮食治疗，但个别患者的DMF/S指数仍然很高。
