Tye L M, Burton A F
Biol Neonate. 1980;38(5-6):265-9. doi: 10.1159/000241375.
Glycogen in fetal mouse tissues was isolated and determined using the anthrone method on gestational days 14-19. Fetal liver showed rapid glycogen deposition after gestational day 17, reaching a value of 46.7 mg/g wet weight on day 19. Heart and placenta showed sizable glycogen stores earlier, with peak values of 21.7 and 12.8 mg/g, respectively, on day 16 which declined thereafter. Lung maintained approximately 10 mg/g days 16-19; gut and brain contained approximately 2 and 4 mg/g, respectively. days 14-19. After injection of dexamethasone into mothers on gestational day 15.5, 16 h prior to assay, the glycogen content of liver increased approximately tenfold, while placental glycogen declined. This indicates that corticosteroids merely accelerate the pattern observed in the normal course of gestation.
在妊娠第14 - 19天，采用蒽酮法对胎鼠组织中的糖原进行分离和测定。胎肝在妊娠第17天后糖原迅速沉积，在第19天达到46.7毫克/克湿重。心脏和胎盘较早出现大量糖原储存，在第16天分别达到峰值21.7毫克/克和12.8毫克/克，此后下降。肺在第16 - 19天维持在约10毫克/克；肠道和大脑分别含有约2毫克/克和4毫克/克。在妊娠第15.5天给母鼠注射地塞米松，在检测前16小时，肝脏的糖原含量增加了约10倍，而胎盘糖原减少。这表明皮质类固醇只是加速了在正常妊娠过程中观察到的模式。
