Sadava D, Elliott K, Bernard B
Biol Neonate. 1980;38(5-6):287-90. doi: 10.1159/000241378.
The developmental progression of thymidine kinase from the electrophoretically slow-migrating 'fetal' forms to the fast-migrating 'adult' form was examined weekly in the serum of 5 premature infants. Only the fetal forms were present up to 32 weeks after conception. The adult form appeared along with the fetal forms until 39 weeks post-conception; thereafter, only the adult form was detected. With respect to post-conceptional age, the timing of the changeover from fetal to adult serum, thymidine kinase was the same in the prematurely born infants as in stillborn infants at an equivalent gestational age.
对5名早产儿血清中胸苷激酶从电泳慢迁移的“胎儿”形式到快迁移的“成人”形式的发育进程进行了每周一次的检测。在受孕后32周之前,仅存在胎儿形式。成人形式与胎儿形式一起出现,直到受孕后39周;此后,仅检测到成人形式。就受孕后年龄而言,早产婴儿从胎儿型血清转变为成人型血清的时间与相同胎龄死产婴儿的情况相同。