Rees G J, Bullimore J A, Lever J V, Pizey N C
Clin Radiol. 1980 Jul;31(4):437-9. doi: 10.1016/s0009-9260(80)80185-1.
Twenty-six patients with non-Hodgkin's lymphoma have received total body irradiation (TBI) as a secondary therapy. A response was achieved with 17 patients, in six of whom it was complete. The actuarial survival rates were 50% at one year and 42% at 30 months. Best results were achieved in those with low grade histology and in those under 60 years of age. Transient marrow toxicity was the only detected significant side-effect of treatment and although it was usually severe there were no serious sequelae. TBI should be considered as a secondary therapy in non-Hodgkin's lymphoma, regardless of previous treatment.
26例非霍奇金淋巴瘤患者接受了全身照射（TBI）作为二线治疗。17例患者有反应，其中6例完全缓解。1年的精算生存率为50%，30个月时为42%。组织学分级低的患者和60岁以下的患者疗效最佳。短暂的骨髓毒性是唯一检测到的显著治疗副作用，尽管通常很严重，但没有严重的后遗症。无论先前的治疗如何，TBI都应被视为非霍奇金淋巴瘤的二线治疗方法。
