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Effect of tylophorine, a major alkaloid of Tylophora indica, on immunopathological and inflammatory reactions.

作者信息

Gopalakrishnan C, Shankaranarayanan D, Nazimudeen S K, Kameswaran L

出版信息

Indian J Med Res. 1980 Jun;71:940-8.

PMID:7419261
Abstract
摘要

相似文献

1
Effect of tylophorine, a major alkaloid of Tylophora indica, on immunopathological and inflammatory reactions.
Indian J Med Res. 1980 Jun;71:940-8.
2
Pharmacological investigations of tylophorine, the major alkaloid of Tylophora indica.娃儿藤碱（印度娃儿藤的主要生物碱）的药理学研究。
Indian J Med Res. 1979 Mar;69:513-20.
3
Left, right, or both? On the configuration of the phenanthroindolizidine alkaloid tylophorine from Tylophora indica.左、右、还是两者兼有？关于印度娃儿藤中菲烷吲哚里西啶生物碱千里光碱的构型。
J Nat Prod. 2013 Feb 22;76(2):275-8. doi: 10.1021/np300838w. Epub 2013 Jan 31.
4
Inhibition of cellular immune responses by Tylophora indica in experimental models.印度娃儿藤在实验模型中对细胞免疫反应的抑制作用。
Phytomedicine. 2001 Sep;8(5):348-55. doi: 10.1078/0944-7113-00055.
5
Tylophorine Abrogates G2/M Arrest Induced by Doxorubicine and Promotes Increased Apoptosis in T47D Breast Cancer Cells.娃儿藤碱消除阿霉素诱导的T47D乳腺癌细胞G2/M期阻滞并促进细胞凋亡增加。
Asian Pac J Cancer Prev. 2018 Nov 29;19(11):3065-3069. doi: 10.31557/APJCP.2018.19.11.3065.
6
Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression.娃儿藤碱通过下调细胞周期蛋白A2的表达使癌细胞停滞于G1期。
Biochem Biophys Res Commun. 2009 Aug 14;386(1):140-5. doi: 10.1016/j.bbrc.2009.05.138. Epub 2009 Jun 6.
7
Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response.一种新型娃儿藤碱类似物通过抑制天然免疫反应对胶原诱导性关节炎的影响。
Arthritis Rheum. 2006 Mar;54(3):877-86. doi: 10.1002/art.21640.
8
Effect of mangostin, a xanthone from Garcinia mangostana Linn. in immunopathological & inflammatory reactions.山竹酮（一种来自莽吉柿的氧杂蒽酮）在免疫病理和炎症反应中的作用。
Indian J Exp Biol. 1980 Aug;18(8):843-6.
9
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.基于菲的娃儿藤碱衍生物作为潜在抗病毒药物的设计、合成及抗病毒评价
J Agric Food Chem. 2010 Dec 8;58(23):12337-42. doi: 10.1021/jf103440s. Epub 2010 Nov 8.
10
Spontaneous plant regeneration in transformed roots and calli from Tylophora indica: Changes in morphological phenotype and tylophorine accumulation associated with transformation by Agrobacterium rhizogenes.娃儿藤转化根和愈伤组织中的自发植株再生：与发根农杆菌转化相关的形态表型变化和娃儿藤碱积累
Plant Cell Rep. 2006 Oct;25(10):1059-66. doi: 10.1007/s00299-006-0164-z. Epub 2006 Apr 12.

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Tylophorine, a phenanthraindolizidine alkaloid isolated from Tylophora indica exerts antiangiogenic and antitumor activity by targeting vascular endothelial growth factor receptor 2-mediated angiogenesis.从 Tylophora indica 中分离得到的 phenanthraindolizidine 生物碱 tylophorine 通过靶向血管内皮生长因子受体 2 介导的血管生成发挥抗血管生成和抗肿瘤活性。
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Brine shrimp cytotoxicity of crude methanol extract and antispasmodic activity of α-amyrin acetate from Tylophora hirsuta wall.厚藤甲醇提取物的卤虫细胞毒性和α-桉叶醇乙酸酯的抗痉挛活性
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Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus.鉴定菲并吲哚里嗪和菲并喹喔啉为新型有效的抗猪传染性胃肠炎病毒和人严重急性呼吸系统综合征冠状病毒的冠状病毒药物。
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