Mizushima Y, Shoji Y, Kaneko K
Int Arch Allergy Appl Immunol. 1980;63(3):338-9. doi: 10.1159/000232645.
An organogermanium was given to young and aged C3H/HeJ mice sensitized by sheep red blood cells, and plaque-forming cells (PFC) in the spleens from the animals were measured. PFC decreased markedly in the aged mice. The organogermanium at an appropriate dose significantly increased the PFC in the aged mice, whereas it did not increase PFC in the young mice. Thus, germanium is considered to restore to some extent the impaired immunoresponses in aged mice.
将一种有机锗给予经绵羊红细胞致敏的年轻和老年C3H/HeJ小鼠，并检测这些动物脾脏中的空斑形成细胞（PFC）。老年小鼠的PFC显著减少。适当剂量的有机锗可显著增加老年小鼠的PFC，而对年轻小鼠的PFC没有增加作用。因此，锗被认为在一定程度上可恢复老年小鼠受损的免疫反应。
