Henderson A, Cumming W J, Williams D O, Hudgson P
J Neurol Sci. 1980 Sep;47(3):425-8. doi: 10.1016/0022-510x(80)90096-9.
We report 3 cases of polymyositis, confirmed by enzyme assay and muscle biopsy, complicated by serious cardiac disease. They showed progressive fascicular block, despite immunosuppressive therapy sufficient to control the skeletal muscle disease, culminating in complete heart block with syncope, requiring the implantation of a pacemaker. In addition, all 3 showed echocardiographic evidence of dilated cardiomyopathy.
我们报告了3例经酶测定和肌肉活检确诊的多发性肌炎，均合并严重心脏疾病。尽管采用了足以控制骨骼肌疾病的免疫抑制治疗，但患者仍出现进行性束支传导阻滞，最终发展为完全性心脏传导阻滞并伴有晕厥，需要植入起搏器。此外，所有3例患者均有超声心动图显示的扩张型心肌病证据。
