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用补充了吡啶甲酸锌或乙酸锌的饲料喂养母鼠,其哺育的幼鼠肝脏和肾脏中的锌浓度。

Zinc concentration of liver and kidneys from rat pups nursing dams fed supplemented zinc dipicolinate or zinc acetate.

作者信息

Evans G W, Johnson E C

出版信息

J Nutr. 1980 Oct;110(10):2121-4. doi: 10.1093/jn/110.10.2121.

Abstract

The zinc concentration of liver and kidneys was determined in rat pups nursing dams given 10 micrograms Zn/ml as either zinc dipicolinate or zinc acetate in water solution during the last week of gestation and for 5 days of lactation. Dams were fed a casein-based diet that contained 8.5 micrograms Zn/g and 2.0 micrograms pyridoxine-HCl/g during this period. The zinc concentrations of both liver and kidneys from the 5-day-old pups nursing dams fed the zinc dipicolinate solution were significantly greater than the zinc concentrations of these tissues from pups nursing dams given a solution of zinc acetate. The results demonstrate that a greater quantity of dietary zinc is transferred from the intestine of the lactating female rat to the pups when zinc is fed in the form of zinc dipicolinate.

摘要

在妊娠最后一周及哺乳期的5天里,给哺乳母鼠饮用含10微克锌/毫升的吡啶甲酸锌或醋酸锌水溶液,测定其仔鼠肝脏和肾脏的锌浓度。在此期间,母鼠喂食以酪蛋白为基础的日粮,其中含8.5微克锌/克和2.0微克盐酸吡哆醇/克。喂食吡啶甲酸锌溶液的哺乳母鼠所哺育的5日龄仔鼠肝脏和肾脏的锌浓度,显著高于喂食醋酸锌溶液的哺乳母鼠所哺育的仔鼠这些组织中的锌浓度。结果表明,当以吡啶甲酸锌的形式喂食锌时,哺乳期雌性大鼠肠道向仔鼠转移的膳食锌量更多。

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