Ledwich J R, Mondragon G A
JAMA. 1980 Nov 14;244(19):2172-4.
Routine clinical and laboratory data were collected from 70 patients with first myocardial infarcts. Compared with the 35 patients whose chest pain duration was less than eight hours, those with chest pain eight hours or longer had higher rises in creatine phosphokinase and SGOT levels, greater summed ST segments (taken from the 12-lead ECG), more transmural infarcts, greater cardiac volumes (measured from subsequent chest roentgenograms), higher temperature rises, and higher WBC counts. These reuslts suggest that pain duration may be an indicator of infarct size.
收集了70例首次发生心肌梗死患者的常规临床和实验室数据。与胸痛持续时间少于8小时的35例患者相比，胸痛持续8小时或更长时间的患者肌酸磷酸激酶和谷草转氨酶水平升高幅度更大、ST段总和（取自12导联心电图）更大、透壁性梗死更多、心脏体积更大（根据随后的胸部X线片测量）、体温升高幅度更大以及白细胞计数更高。这些结果表明，疼痛持续时间可能是梗死面积的一个指标。
