Brownstein S, Codere F, Jackson W B
Ophthalmology. 1980 Mar;87(3):259-62. doi: 10.1016/s0161-6420(80)35245-7.
A 52-year-old man experienced chronic blepharoconjunctivitis of the right eye of the three years' duration that was unresponsive to medications. Conjunctival cytologic examinations suggested carcinoma and this was confirmed. However, only a full-thickness eyelid biopsy established that the tumor was a sebaceous carcinoma. We discuss the importance of considering this condition in all cases of unilateral, persistent, or recurrent eyelid inflammation resistant to the usual therapy; the diagnostic value of conjunctival scrapings and full-thickness lid biopsy; and the necessity of interpretation of the biopsy material by a pathologist experienced with, and alerted to look for, this neoplasm. Early recognition of sebaceous carcinoma followed by prompt adequate therapy should improve the survival of patients with this rare but malignant tumor.
一名52岁男性右眼患有慢性睑结膜炎，病程长达三年，药物治疗无效。结膜细胞学检查提示为癌，后经证实。然而，只有通过全层眼睑活检才确定肿瘤为皮脂腺癌。我们讨论了在所有单侧、持续性或复发性眼睑炎症且常规治疗无效的病例中考虑这种疾病的重要性；结膜刮片和全层眼睑活检的诊断价值；以及由熟悉并警惕寻找这种肿瘤的病理学家对活检材料进行解读的必要性。早期识别皮脂腺癌并及时进行充分治疗应能提高这种罕见但恶性肿瘤患者的生存率。
