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在离体灌注犬肺中微血管压力的直接测量。

Direct measurement of microvascular pressures in the isolated perfused dog lung.

作者信息

Bhattacharya J, Staub N C

出版信息

Science. 1980 Oct 17;210(4467):327-8. doi: 10.1126/science.7423192.

DOI:10.1126/science.7423192
PMID:7423192
Abstract

Microvascular pressures in the pulmonary circulation were measured under the pleural surface of the isolated perfused dog lung by the servo-null technique. Strong glass micropipettes with short beveled tips were used, with a suction ring to stabilize the lung's surface. Of the total vascular resistance, 45 percent was in the alveolar wall capillaries themselves. Most of the remaining resistance was in the arterioles. There was negligible pressure drop in venules with diameters larger than 20 micrometers.

摘要

采用伺服零位技术,在离体灌注犬肺的胸膜表面测量肺循环中的微血管压力。使用带有短斜尖的坚固玻璃微量移液器,并带有一个吸引环以稳定肺表面。在总血管阻力中,45% 存在于肺泡壁毛细血管本身。其余大部分阻力存在于小动脉中。直径大于 20 微米的小静脉中的压力降可忽略不计。

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