Ahmed M A, Abdel Wahab S M, Abdel Malik M O, Abdel Gadir A M, Salih S Y, Omer A, Al Hassan A M
Trop Geogr Med. 1980 Jun;32(2):106-11.
A small outbreak of louse-borne relapsing fever in Khartoum (May-June 1974) provided material for a clinico-pathological study. The history of the disease in the Sudan is reviewed and the clinical and laboratory findings in 32 patients are presented. Fever, headache, jaundice, epistaxis and hepatosplenomegaly were the commonest clinical findings; thrombocytopenia was detected in 93% of cases. Although elevated levels of fibrin degradation products were found in most patients, disseminated intravascular coagulation could not be diagnosed. Hepatocellular derangement was found in 68% of cases, while 78% had high blood urea. In five autopsied bodies there was bronchopneumonia, interstitial edema with focal myocardial fibrosis, hepatic necrosis, splenic infarcts, increase in size and cellularity of the glomeruli and brain edema and congestion. Intracranial haemorrhage was found in three of the autopsied cases.
1974年5月至6月在喀土穆发生的一起小规模虱传回归热疫情为一项临床病理研究提供了素材。本文回顾了苏丹的该病病史，并介绍了32例患者的临床和实验室检查结果。发热、头痛、黄疸、鼻出血和肝脾肿大是最常见的临床表现；93%的病例检测到血小板减少。尽管大多数患者的纤维蛋白降解产物水平升高，但无法诊断为弥散性血管内凝血。68%的病例发现肝细胞紊乱，78%的患者血尿素升高。在5具尸检尸体中，发现有支气管肺炎、伴有局灶性心肌纤维化的间质性水肿、肝坏死、脾梗死、肾小球大小和细胞数量增加以及脑水肿和充血。在3例尸检病例中发现了颅内出血。
