Salih S Y, Mustafa D, Abdel Wahab S M, Ahmed M A, Omer A
Trans R Soc Trop Med Hyg. 1977;71(1):43-8. doi: 10.1016/0035-9203(77)90206-1.
Louse-borne relapsing fever seems to have become endemic in the southern Sudan. The epidemic history of the disease in the Sudan is reviewed. We have studied 363 Sudanese patients involved in an outbreak of louse-borne relapsing fever in Khartoum (Sudan) between January and June 1974. 318 of the 363 patients were new immigrants from the soughern Sudan to Khartoum. The clinical presentation varied. The common clinical fetures of the disease were: fever (94%), headache (85%), hepatosplenomegaly (74%), body and joint pains (66%), abdominal pain and tenderness (63%), jaundice (46%) and epistaxis (40%). Thrombocytopenia was common. Biochemical evidence of hepatocellular and renal damage was present in most patients. The mortality rate was 5-5% with treatment. Post-mortem examination was performed on six cases. The organs predominantly involved were the liver, spleen, brain and lungs. The common causes of death were severe hepatic damage, lobar pneumonia, subarachnoid haemorrhage and splenic rupture.
虱传回归热似乎已在苏丹南部成为地方病。本文回顾了苏丹该疾病的流行病史。我们研究了1974年1月至6月间在苏丹喀土穆爆发的虱传回归热疫情中的363例苏丹患者。363例患者中有318例是从苏丹南部新移民到喀土穆的。临床表现各异。该疾病常见的临床特征为：发热（94%）、头痛（85%）、肝脾肿大（74%）、全身及关节疼痛（66%）、腹痛及压痛（63%）、黄疸（46%）和鼻出血（40%）。血小板减少很常见。大多数患者存在肝细胞和肾损伤的生化证据。经治疗死亡率为5 - 5%。对6例患者进行了尸检。主要受累器官为肝脏、脾脏、脑和肺。常见死亡原因是严重肝损伤、大叶性肺炎、蛛网膜下腔出血和脾破裂。
