Hase U, Reulen H J, Meinig G, Schürmann K
Acta Neurochir (Wien). 1978;45(1-2):1-13. doi: 10.1007/BF01774379.
Measurements of intracranial pressure by ventricular catheter were performed in 47 patients with severe head injuries. Thirty-three patients with decompressive operations such as osteoclastic craniotomy and dilatation by means of duraplastic have been compared with 14 patients with closed heads with regard to volume pressure response (intracranial elasticity). This was determined either by intraventricular injection of 2ml saline or by drainage of cerebrospinal fluid. The examination clearly shows that patients with closed heads have a much higher intracranial elasticity than patients who have decompressive operations, so that in the first group minor differences of the intracranial volume cause extreme deviations of the intracranial pressure. Therefore, the decompressive operation has been advised in severe head injuries with increased intracranial pressure as a measure additional to high dose dexamethasone therapy and hyperventilation.
对47例重型颅脑损伤患者进行了脑室导管颅内压测量。将33例行去骨瓣开颅术和硬脑膜成形术扩张等减压手术的患者与14例闭合性颅脑损伤患者在容量压力反应（颅内弹性）方面进行了比较。这是通过脑室内注入2ml生理盐水或脑脊液引流来确定的。检查清楚地表明，闭合性颅脑损伤患者的颅内弹性比接受减压手术的患者高得多，因此在第一组中，颅内体积的微小差异会导致颅内压的极端偏差。因此，对于颅内压升高的重型颅脑损伤患者，建议在大剂量地塞米松治疗和过度通气之外，将减压手术作为一项附加措施。
