Guillamondegui O M, Oliver B, Hayden R
Am J Surg. 1980 Oct;140(4):560-2. doi: 10.1016/0002-9610(80)90212-3.
From 1971 through 1975, 104 patients with squamous carcinoma of the anterior and anterolateral floor of the mouth underwent surgery, irradiation therapy or a combination of both with the purpose of eliminating their tumors. No patient had received treatment before, and this effort was considered primary and definitive. Fifty-five patients were free of cancer at the time of this analysis, 21 had died of intercurrent disease or new primary tumors, 1 patient was alive although suffering from another primary cancer, and in 27 patients the treatment failed and they died of recurrent carcinoma of the head and neck or with distant metastases. The ultimate determinate rate of control for all stages of disease was 66 percent. A rational approach to the problem of selecting a particular form of treatment for patients with cancer of the anterior floor of the mouth in different clinical manifestations is presented.
从1971年到1975年，104例口腔前庭及前外侧部鳞状癌患者接受了手术、放射治疗或两者联合治疗，目的是消除肿瘤。所有患者此前均未接受过治疗，此次治疗被视为初次根治性治疗。在本次分析时，55例患者无癌生存，21例死于并发疾病或新发原发性肿瘤，1例虽患有另一种原发性癌症但仍存活，27例患者治疗失败，死于头颈部复发性癌或远处转移。疾病各阶段的最终控制率为66%。本文提出了一种针对不同临床表现的口腔前庭癌患者选择特定治疗方式问题的合理方法。
