Dennhardt R, Konder H
Anaesthesist. 1980 Apr;29(4):25-6.
Following continuous epidural anaesthesia, the urine volumes of patients were collected. By gas-chromatographic analysis 6 metabolites of bupivacaine were identified: 1. Desbutylbupivacaine; 2. 3'-Hydroxy-bupivacaine; 3. N-Butyl-pipecolyl-2-amide; 4. and 5. monohydroxylated isomeres on the piperidine ring; 6. 4'-Hydroxy-bupivacaine.
在连续硬膜外麻醉后，收集患者的尿量。通过气相色谱分析，鉴定出布比卡因的6种代谢产物：1. 去丁基布比卡因；2. 3'-羟基布比卡因；3. N-丁基哌啶-2-酰胺；4. 和5. 哌啶环上的单羟基异构体；6. 4'-羟基布比卡因。
