茶碱对食管下括约肌压力的影响。
The effect of theophylline on the lower esophageal sphincter pressure.
作者信息
Stein M R, Towner T G, Weber R W, Mansfield L E, Jacobson K W, McDonnell J T, Nelson H S
出版信息
Ann Allergy. 1980 Oct;45(4):238-41.
PMID:7425397
Abstract
The effects of theophylline on lower esophageal sphincter pressure (LESP) were studied on four normal volunteers and six asthmatics with symptoms of gastroesophageal reflux (GER). Manometric evaluations of LESP were obtained before and after an intravenous dose of aminophylline. All subjects had therapeutic theophylline levels at the time of the second measurement of LESP and a significant decrease in LESP occurred in normal and asthmatic volunteers.
摘要
在四名正常志愿者和六名有胃食管反流（GER）症状的哮喘患者身上研究了茶碱对下食管括约肌压力（LESP）的影响。在静脉注射氨茶碱之前和之后对LESP进行了测压评估。在第二次测量LESP时，所有受试者的茶碱水平均处于治疗范围，并且正常志愿者和哮喘志愿者的LESP均出现了显著下降。
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