O'Hara P J, Brewster D C, Darling R C, Hallett J W
Arch Surg. 1980 Oct;115(10):1156-8. doi: 10.1001/archsurg.1980.01380100008002.
The oculopneumoplethysmography (OPPG) test has been proposed as an effective method to identify significant carotid artery stenoses. To evaluate the clinical relevance of OPPG testing performed without carotid compression, the results of the preoperative OPPG studies, intraoperative pressure gradient measurements, and intraoperative "stump" pressure determinations were correlated retrospectively with the severity of the carotid lesions. Patients with positive OPPG test results had a mean pressure gradient of 44 mm Hg, whereas those patients with negative results had a mean gradient of 20 mm Hg. Of the patients with true-positive OPPG test results, 94% (29/31) had lesions causing at least 70% diameter reduction. However, overall accuracy of OPPG testing in this series was only 63% (33/52), as 81% (17/21) of the patients with false-negative OPPG test results also had tight lesions. Without carotid compression, OPPG testing was not useful in predicting intraoperative stump pressure. The OPPG test reflects a balance between the severity of the carotid stenosis and the adequacy of compensatory collateral flow. A positive OPPG test result is reliable in identifying those patients at greatest risk from their carotid arterial lesion. Although a negative OPPG test result does not exclude a tight stenosis, it does provide information with regard to its hemodynamic significance.
眼体积描记法（OPPG）测试已被提议作为一种识别严重颈动脉狭窄的有效方法。为了评估在不进行颈动脉压迫的情况下进行的OPPG测试的临床相关性，对术前OPPG研究结果、术中压力梯度测量结果以及术中“残端”压力测定结果与颈动脉病变的严重程度进行了回顾性关联分析。OPPG测试结果为阳性的患者平均压力梯度为44毫米汞柱，而测试结果为阴性的患者平均梯度为20毫米汞柱。在OPPG测试结果为真阳性的患者中，94%（29/31）有导致直径至少减少70%的病变。然而，该系列中OPPG测试的总体准确率仅为63%（33/52），因为81%（17/21）OPPG测试结果为假阴性的患者也有严重病变。在不进行颈动脉压迫的情况下，OPPG测试在预测术中残端压力方面并无用处。OPPG测试反映了颈动脉狭窄的严重程度与代偿性侧支血流充足程度之间的平衡。OPPG测试结果为阳性在识别那些因颈动脉病变而风险最大的患者方面是可靠的。虽然OPPG测试结果为阴性并不能排除严重狭窄，但它确实提供了有关其血流动力学意义的信息。
