Kozliuk A S
Arkh Patol. 1980;42(9):34-40.
Comparative pathology of respiratory M. pneumoniae infection in rats, rabbits, and monkeys was studied. The time course of pathological processes in the lungs was investigated by light and immunoluminescent microscopy. Electron microscopy showed M. pneumoniae to be fixed on the surface of the epithelium of the upper respiratory tract; mycoplasmal penetration into a alveolocytes and macrophages, the development of degenerative changes, and death of the affected cells were followed. Multiplication of mycoplasmas in the septal stroma leading to alternative lesions of the endothelium of capillaries and other aerohematic barrier structures was proved. The genesis of these processes is discussed.
研究了大鼠、兔子和猴子呼吸道肺炎支原体感染的比较病理学。通过光学显微镜和免疫荧光显微镜研究了肺部病理过程的时间进程。电子显微镜显示肺炎支原体固定在上呼吸道上皮表面；追踪了支原体侵入肺泡细胞和巨噬细胞、退行性变化的发展以及受影响细胞的死亡。证实了支原体在间质基质中的增殖导致毛细血管内皮和其他气血屏障结构的交替性病变。讨论了这些过程的发生机制。
