C3a对成纤维细胞的细胞溶解作用。
Cytolysis of fibroblasts by C3a.
作者信息
Temple A, Allison A C
出版信息
Br J Cancer. 1980 Jul;42(1):21-5. doi: 10.1038/bjc.1980.198.
Abstract
C3a was found to be more cytolytic to transformed than to primary fibroblast cultures from mouse and man. Fibroblasts made quiescent with caffeine were lysed by the same concentrations of C3a as untreated cells. These findings may have implications in tumour immunity.
摘要
研究发现，C3a对来自小鼠和人类的转化成纤维细胞培养物的细胞溶解作用比对原代成纤维细胞培养物更强。用咖啡因处理后进入静止状态的成纤维细胞，在相同浓度的C3a作用下会像未处理的细胞一样被裂解。这些发现可能对肿瘤免疫有影响。
相似文献
1
Cytolysis of fibroblasts by C3a.C3a对成纤维细胞的细胞溶解作用。
Br J Cancer. 1980 Jul;42(1):21-5. doi: 10.1038/bjc.1980.198.
2
Cytolytic effects of the complement cleavage product, C3a.补体裂解产物C3a的细胞溶解作用。
Br J Cancer. 1976 Dec;34(6):626-34. doi: 10.1038/bjc.1976.223.
3
Production of the complement cleavage product, C3a, by activated macrophages and its tumorolytic effects.活化巨噬细胞产生补体裂解产物C3a及其溶瘤作用。
Clin Exp Immunol. 1978 Mar;31(3):512-7.
4
Inability of the C3a anaphylatoxin to promote cellular lysis.C3a过敏毒素无法促进细胞溶解。
Nature. 1980 Jan 3;283(5742):78-80. doi: 10.1038/283078a0.
5
Inhibition of in vitro natural killer activity by the third component of complement: role for the C3a fragment.补体第三成分对体外自然杀伤活性的抑制作用：C3a片段的作用
Proc Natl Acad Sci U S A. 1982 Oct;79(19):6003-7. doi: 10.1073/pnas.79.19.6003.
6
7
The effect of dexamethasone on the functioning of C3 receptor sites on the surfaces of human fibroblasts.地塞米松对人成纤维细胞表面C3受体位点功能的影响。
Virchows Arch B Cell Pathol. 1976 Dec 2;22(4):315-21. doi: 10.1007/BF02889225.
8
The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments.白色念珠菌分泌的蛋白Pra1通过广泛靶向并阻断补体C3及其激活片段来破坏宿主防御。
Mol Immunol. 2018 Jan;93:266-277. doi: 10.1016/j.molimm.2017.07.010. Epub 2017 Aug 30.
9
A monoclonal antibody against human complement component C3: the production of C3 by human cells in vitro.一种抗人补体成分C3的单克隆抗体：人细胞在体外产生C3的情况
Eur J Immunol. 1981 Feb;11(2):140-6. doi: 10.1002/eji.1830110215.
10
SV40-transformed human cells fail to grow in zinc concentrations which permit normal human fibroblast proliferation.SV40转化的人类细胞在允许正常人成纤维细胞增殖的锌浓度下无法生长。
J Cell Physiol. 1982 Jan;110(1):17-22. doi: 10.1002/jcp.1041100104.
本文引用的文献
1
Inability of the C3a anaphylatoxin to promote cellular lysis.C3a过敏毒素无法促进细胞溶解。
Nature. 1980 Jan 3;283(5742):78-80. doi: 10.1038/283078a0.
2
Complement as a mediator of inflammation. 3. Purification of the activity with anaphylatoxin properties generated by interaction of the first four components of complement and its identification as a cleavage product of C'3.补体作为炎症介质。3. 具有过敏毒素特性的活性物质的纯化，该活性物质由补体前四种成分相互作用产生，并鉴定为C'3的裂解产物。
J Exp Med. 1967 Dec 1;126(6):1027-48. doi: 10.1084/jem.126.6.1027.
3
Independent and consecutive action of the complement components C5, C6 and C7 in immune hemolysis. I. Preparation of EAC1-5 with purified guinea pig C3 and C5.补体成分C5、C6和C7在免疫溶血中的独立连续作用。I. 用纯化的豚鼠C3和C5制备EAC1-5 。
Immunochemistry. 1970 Dec;7(12):955-65. doi: 10.1016/0019-2791(70)90002-9.
4
The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement.从人补体的第三和第五成分中衍生出两种不同的过敏毒素活性。
J Exp Med. 1968 Feb 1;127(2):371-86. doi: 10.1084/jem.127.2.371.
5
Cutaneous responses to human C 3 anaphylatoxin in man.人类对人C3过敏毒素的皮肤反应。
Clin Exp Immunol. 1972 May;11(1):13-20.
6
Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase.人血浆过敏毒素灭活剂：其作为羧肽酶的分离与特性鉴定
J Clin Invest. 1970 Dec;49(12):2427-36. doi: 10.1172/JCI106462.
7
In vitro synthesis of factor B of the alternative pathway of complement activation by mouse peritoneal macrophages.小鼠腹腔巨噬细胞对补体激活替代途径中B因子的体外合成
Eur J Immunol. 1976 Jun;6(6):393-8. doi: 10.1002/eji.1830060604.
8
Effects of activated complement components on enzyme secretion by macrophages.活化补体成分对巨噬细胞酶分泌的影响。
Immunology. 1976 Nov;31(5):781-8.
9
Ability of activated complement components to induce lysosomal enzyme release from macrophages.活化补体成分诱导巨噬细胞释放溶酶体酶的能力。
Nature. 1976 May 6;261(5555):48-9. doi: 10.1038/261048a0.
10
Cytolytic effects of the complement cleavage product, C3a.补体裂解产物C3a的细胞溶解作用。
Br J Cancer. 1976 Dec;34(6):626-34. doi: 10.1038/bjc.1976.223.
Zotero 插件