Harrison R F, Mansfield M D
Br J Obstet Gynaecol. 1980 Aug;87(8):695-704. doi: 10.1111/j.1471-0528.1980.tb04603.x.
Mean maternal plasma levels of testosterone, androstenedione, and 5 alpha-dihydrotestosterone were established from 4 to 16 weeks gestation from twice-weekly blood samples taken from 15 pregnant women. All three hormone levels were raised when compared with the non-pregnant state. There were significant differences in mean maternal plasma testosterone levels at 4 to 5 and 7 to 8 weeks gestation, when comparing women carrying male and female fetuses. Androstenedione levels in a twin pregnancy were increased throughout and testosterone levels were more than 1 SD above the mean from week 15. Steroid levels fell late in the two women who aborted. Hormone levels in three women being given progestogens were within normal limits.
从15名孕妇每周两次采集的血样中，测定了妊娠4至16周期间母体血浆中睾酮、雄烯二酮和5α - 双氢睾酮的平均水平。与非妊娠状态相比，所有三种激素水平均升高。比较怀有男胎和女胎的女性时，妊娠4至5周和7至8周时母体血浆睾酮平均水平存在显著差异。双胎妊娠中雄烯二酮水平持续升高，睾酮水平从第15周起高于平均值超过1个标准差。两名流产女性后期类固醇水平下降。三名接受孕激素治疗的女性激素水平在正常范围内。
