接受溴化三苯乙烯反式异构体的（C3H×RIII）F1小鼠的乳腺癌发生
Mammary carcinogenesis in (C3H x RIII)F1 mice which receive the trans isomer of a brominated triphenylethylene.
作者信息
Rudali G, Vives C, Guggiari M, Montes-Rendon A
出版信息
Biomedicine. 1980 Jul-Aug;33(4):126-8.
PMID:7426677
Abstract
The trans isomer of a bromotriphenylethylene (TBP) inhibits spontaneous mammary carcinogenesis in (C3H x RIII)F1 females, which received a diet containing 20 ppm of the chemical: intact, spayed, and spayed and pituitary implanted animals. Mammary carcinogenesis is inhibited even if the administration of the compound starts late in life. TBP has no activity on mammary carcinogenesis of castrated males implanted with an ovary.
摘要
溴代三苯乙烯（TBP）的反式异构体可抑制（C3H×RIII）F1雌性小鼠的自发性乳腺癌发生，这些小鼠食用含20 ppm该化学物质的饲料：完整小鼠、去势小鼠以及去势并植入垂体的动物。即使在生命后期开始给予该化合物，乳腺癌发生仍会受到抑制。TBP对植入卵巢的去势雄性小鼠的乳腺癌发生没有作用。
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