Sokoloff L
Bull Schweiz Akad Med Wiss. 1980 Apr;36(1-3):71-91.
The results of studies with the (14C)deoxyglucose technique unequivocally establish that local energy metabolism in cerebral tissues is, as in other tissues, closely coupled to local functional activity. Stimulation of local functional activity increases the local rate of glucose utilization; reduced functional activity depresses it. Local cerebral blood flow is normally distributed among the cerebral structures in almost exact proportion to their rates of glucose utilization and changes together with local glucose consumption in response to altered local functional activity. These results demonstrate that the level of functional activity in the structural and functional components of the central nervous syetem regulates the local rate of energy metabolism, and local blood flow is adjusted to the local metabolic demand.
用（14C）脱氧葡萄糖技术进行的研究结果明确证实，与其他组织一样，脑组织中的局部能量代谢与局部功能活动密切相关。局部功能活动的刺激会增加局部葡萄糖利用率；功能活动的降低则会抑制它。局部脑血流量通常在脑结构之间以几乎与它们的葡萄糖利用率精确成比例的方式分布，并随着局部功能活动的改变而与局部葡萄糖消耗一起变化。这些结果表明，中枢神经系统结构和功能成分中的功能活动水平调节局部能量代谢率，并且局部血流量会根据局部代谢需求进行调整。
