兔小肠对动脉周围神经刺激的运动反应机制。
The mechanism of the motor response to periarterial nerve stimulation in the small intestine of the rabbit.
作者信息
Barthó L, Szolcsányi J
出版信息
Br J Pharmacol. 1980 Oct;70(2):193-5. doi: 10.1111/j.1476-5381.1980.tb07924.x.
Abstract
In the presence of guanethidine, periarterial nerve stimulation caused a frequency-dependent motor response in the rabbit isolated ileum. Tachyphylaxis to capsaicin greatly diminished the effect of periarterial stimulation; the remaining portion of the contractile response was susceptible to hexamethonium. The motor effect of periarterial stimulation is mediated by two different mechanisms: one via parasympathetic preganglionic nerves and the other sensitive to capsaicin.
摘要
在胍乙啶存在的情况下，动脉周围神经刺激在兔离体回肠中引起频率依赖性运动反应。对辣椒素的快速耐受性大大降低了动脉周围刺激的效果；收缩反应的其余部分对六甲铵敏感。动脉周围刺激的运动效应由两种不同机制介导：一种通过副交感神经节前神经，另一种对辣椒素敏感。
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