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兔小肠对动脉周围神经刺激的运动反应机制。

The mechanism of the motor response to periarterial nerve stimulation in the small intestine of the rabbit.

作者信息

Barthó L, Szolcsányi J

出版信息

Br J Pharmacol. 1980 Oct;70(2):193-5. doi: 10.1111/j.1476-5381.1980.tb07924.x.

DOI:10.1111/j.1476-5381.1980.tb07924.x
PMID:7426832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2044320/
Abstract

In the presence of guanethidine, periarterial nerve stimulation caused a frequency-dependent motor response in the rabbit isolated ileum. Tachyphylaxis to capsaicin greatly diminished the effect of periarterial stimulation; the remaining portion of the contractile response was susceptible to hexamethonium. The motor effect of periarterial stimulation is mediated by two different mechanisms: one via parasympathetic preganglionic nerves and the other sensitive to capsaicin.

摘要

在胍乙啶存在的情况下，动脉周围神经刺激在兔离体回肠中引起频率依赖性运动反应。对辣椒素的快速耐受性大大降低了动脉周围刺激的效果；收缩反应的其余部分对六甲铵敏感。动脉周围刺激的运动效应由两种不同机制介导：一种通过副交感神经节前神经，另一种对辣椒素敏感。

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引用本文的文献

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Capsaicin-sensitive afferent neurones and gastrointestinal propulsion in the rat.辣椒素敏感传入神经元与大鼠胃肠道推进运动
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3
Extrinsic origin of the capsaicin-sensitive innervation of rat duodenum: possible involvement of calcitonin gene-related peptide (CGRP) in the capsaicin-induced activation of intramural non-adrenergic non-cholinergic neurons.大鼠十二指肠辣椒素敏感神经支配的外在起源：降钙素基因相关肽（CGRP）可能参与辣椒素诱导的壁内非肾上腺素能非胆碱能神经元的激活。
Naunyn Schmiedebergs Arch Pharmacol. 1986 Oct;334(2):172-80. doi: 10.1007/BF00505818.
4
Distribution of substance P in the enteric plexuses of the small intestine of the platypus, Ornithorhynchus anatinus.鸭嘴兽（Ornithorhynchus anatinus）小肠肠丛中P物质的分布。
Cell Tissue Res. 1989 Mar;255(3):663-7. doi: 10.1007/BF00218806.

本文引用的文献

1
On the nature of inhibition in the intestine.论肠道抑制的本质。
J Physiol. 1930 Sep 18;70(2):145-57. doi: 10.1113/jphysiol.1930.sp002683.
2
Effect of guanethidine in revealing cholinergic sympathetic fibres.胍乙啶在显示胆碱能交感神经纤维方面的作用。
Br J Pharmacol Chemother. 1961 Oct;17(2):245-60. doi: 10.1111/j.1476-5381.1961.tb01285.x.
3
Studies on sympathetic mechanisms in isolated intestinal and vas deferens preparations.离体肠管和输精管标本中交感神经机制的研究。
Br J Pharmacol Chemother. 1962 Aug;19(1):85-98. doi: 10.1111/j.1476-5381.1962.tb01429.x.
4
The inhibitory action of the sympathetic nerves on the smooth muscle of the rabbit gut, its reversal by reserpine and restoration by catechol amines and by DOPA.交感神经对兔肠道平滑肌的抑制作用，利血平对其的逆转作用以及儿茶酚胺和多巴对其的恢复作用。
J Physiol. 1961 Apr;156(1):17-34. doi: 10.1113/jphysiol.1961.sp006655.
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The development of the adrenergic fibre.肾上腺素能纤维的发育。
Br J Pharmacol Chemother. 1968 Mar;32(3):575-82. doi: 10.1111/j.1476-5381.1968.tb00457.x.
6
Effects of tetrodotoxin on innervated smooth muscle preparations.河豚毒素对有神经支配的平滑肌制剂的作用。
Br J Pharmacol Chemother. 1967 Mar;29(3):259-79. doi: 10.1111/j.1476-5381.1967.tb01958.x.
7
Do some sympathetic neurones synthesize and release both noradrenaline and acetylcholine?是否有一些交感神经元既能合成和释放去甲肾上腺素又能合成和释放乙酰胆碱？
Prog Neurobiol. 1978;11(3-4):205-22. doi: 10.1016/0301-0082(78)90013-8.