Vesical leukoplakia.

Thirty-two patients with vesical leukoplakia have been seen in the St Peter's group of hospitals during the past 20 years. Twenty-five (78%) were men and 7 (22%) women with an average at diagnosis of 55 years. Seventeen (53%) had a history of chronic or recurrent urinary infection whilst 9 (28%) had previously developed bladder stones. Nine patients (28%) have so far developed a carcinoma of the bladder in association with the leukoplakia and, of these 4 are dead, 2 having died of metastatic disease and 2 in the immediate post-operative period. Eight of the 9 malignancies were squamous carcinomas.