Padrón R S, Nodarse M
Br J Urol. 1980 Jun;52(3):226-8. doi: 10.1111/j.1464-410x.1980.tb02964.x.
A clinical evaluation of the effects of the antidepressive drug amitriptyline on the semen of 20 infertile men with oligoasthenozoospermia was carried out. Quantitative assessment of semen in the whole group showed significantly higher sperm counts, an increased proportion with normal sperm morphology and an increased semen volume after treatment, with a high positive correlation between sperm count before and after treatment. Individual qualitative evaluation showed an increased sperm count in 50% and increased motility in 35% of patients. It would seem that amitriptyline has a beneficial effect on semen in some of these patients.
对20名患有少弱精子症的不育男性，开展了抗抑郁药物阿米替林对其精液影响的临床评估。对全组精液的定量评估显示，治疗后精子计数显著升高、正常精子形态比例增加且精液量增多，治疗前后精子计数之间存在高度正相关。个体定性评估显示，50%的患者精子计数增加，35%的患者精子活力增加。阿米替林似乎对其中一些患者的精液有有益影响。
